Organized by Nanjing University, 2025 2nd International Conference on Computational Modeling and Applied Mathematics (CMAM 2025) is to be held in Nanjing from August 1-3, 2025. The conference will provide an international platform for experts, professors, scholars, engineers, etc. from higher educational institutions, scientific research institutes, enterprises and institutions of domestic and foreign countries to share their scientific experience, expand their professional networks, exchange new ideas and present their research results face-to-face and present their research results, to discuss the key challenges and research directions of the development of this field, and to promote scientific and technological innovation.