2025 12th International Conference on Biomedical and Bioinformatics Engineering (ICBBE 2025). ICBBE 2025 will be held during November 27-30, 2025 at The University of Tokyo, Tokyo, Japan. ICBBE 2025 is supported by Ritsumeikan University, Taipei University of Technology, East China Normal University, Shanghai Key Laboratory of Multidimensional Information Processing, the Biology and Bioinformatics Society (BBS). Previously, the papers of ICBBE have been published in the Conference Proceedings by ACM and indexed by Ei Compendex and Scopus for 9 years.