Welcome to International Conference on AI-Powered Computing Systems (ICAIPCS - 25), an exciting event that strives to bring together all stakeholders in the discipline of AI-Powered Computing Systems to promote authentic and accelerated scientific research progress. At our conference, participants, keynote speakers, presenters, volunteers, and others will gain access to best-in-class resources, infrastructure, and opportunities to help them achieve their professional objectives, no matter how diverse and varied they may be.